Characterising and Visualising Cross-Presenting Dendritic Cells Following Cutaneous Vaccinia Infection

Effective priming of herpes simplex virusspecific CD8 T cells in vivo does not require infected dendritic cells

PG Whitney, C Makhlouf, B MacLeod, JZ Ma, E Gressier, M Greyer, K Hochheiser, A Bachem, A Zaid, D Voehringer, WR Heath, MV Wagle, I Parish, TA Russell, SA Smith, DC Tscharke, T Gebhardt, S Bedoui

2018-02-01

Resolution of virus infections depends on the priming of virus-specific CD8⁺ T cells by dendritic cells (DC). While thi..

T Cell Help Amplifies Innate Signals in CD8 DCs for Optimal CD8 T Cell Priming

M Greyer, PG Whitney, AT Stock, GM Davey, C Tebartz, A Bachem, JD Mintern, RA Strugnell, SJ Turner, T Gebhardt, M O'Keeffe, WR Heath, S Bedoui

2016-01-26

DCs often require stimulation from CD4⁺ T cells to propagate CD8⁺ T cell responses, but precisely how T cell..